SciTech Chronicles. . . . . . . . .Mar 22nd, 2025

https://bit.ly/stc032225

#amygdala #PTSD #dorsal #lateral #HyperNIR #spectral #composition #hyperspectral #neurodegenerative #blood-brain #meningeal #lymphatics #Sense #skin-to-skin #oxytocin #adolescents #Doggerland #peat #Paleorecords #meltwater

#Neurodegenerative diseases, including #Alzheimer’s, #Parkinson’s disease, and amyotrophic lateral sclerosis (ALS), result from the progressive decline of #brain and nervous system functions, primarily due to aging.
#Biotechnology #Neuroscience #sflorg
https://www.sflorg.com/2025/02/btech02032501.html

Researchers at the Broad Institute of MIT and Harvard have developed a gene-editing treatment for #prion disease that extends lifespan by about 50 percent in a mouse model of the fatal #neurodegenerative condition.
#Neuroscience #Genetics #sflorg
https://www.sflorg.com/2025/01/ns01142501.html

Protein aggregation is typical of various #neurodegenerative diseases such as #Alzheimer’s, #Parkinson’s and #prion diseases such as #Creutzfeld-Jakob disease.
#Neuroscience #sflorg
https://www.sflorg.com/2025/01/ns01062502.html

https://www.sciencealert.com/study-of-500000-medical-records-links-viruses-with-alzheimers-again-and-again “Strikingly, #vaccines are currently available for some of these viruses, including influenza, shingles (varicella-zoster), and pneumonia," the researchers wrote in their paper published last year.

"Although vaccines do not prevent all cases of illness, they are known to dramatically reduce hospitalization rates. This evidence suggests that vaccination may mitigate some risk of developing #neurodegenerative disease."

Queen Sofia attended the International Congress on Neurodegenerative Diseases in Lisbon. Co-organised by the Queen Sofia Foundation it highlights advances in research on neurodegenerative diseases https://www.inbella.com/731147/queen-sofia-attended-the-international-congress-on-neurodegenerative-diseases-in-lisbon-co-organised-by-the-queen-sofia-foundation-it-highlights-advances-in-research-on-neurodegenerative-diseases/ #advances #attended #Congress #Coorganised #diseases #EventsAndAppearances #Foundation #Gossip #Highlights #international #Lisbon #Neurodegenerative #QUEEN #Research #Royal #RoyalFamilies #RoyalGossip #Royals #RoyalsGossip #Sofia

From Cancer to Brain Health: A New Alzheimer’s Treatment Emerges
https://scitechdaily.com/from-cancer-to-brain-health-a-new-alzheimers-treatment-emerges/
#Cancer #BrainHealth #Alzheimer’s #Treatment #IDO1Inhibitors #Neurodegenerative #turkey

Five ways the brain can age: 50,000 scans reveal possible patterns of damage
https://www.nature.com/articles/d41586-024-02692-z #aging #brain #neurodegenerative #DeepLearning #BrainAtrophy

#Rare #Genetic #Variants Are Curiously #Connected With Being #LeftHanded

Learning how these #variations make left-handers different in other ways could help solve #mysteries such as how #genes can make people more likely to have #neurodevelopmental #disorders or develop #neurodegenerative #diseases.

#Women #Transgender #LGBTQ #LGBTQIA #Handedness #Autism #GenderIdentity

https://www.sciencealert.com/rare-genetic-variants-are-curiously-connected-with-being-left-handed

University of Queensland researchers have found targeting #amyloid #plaque in the #brain is not essential for #ultrasound to deliver #cognitive improvement in #neurodegenerative disorders.
#Psychiatry #sflorg
https://www.sflorg.com/2024/04/pscy04022402.html

#Parkinsons Can Now Be Detected Through the Skin. New test identifies Parkinson’s by a protein rather than waiting for symptoms that can take years to appear https://www.msn.com/en-us/health/other/parkinson-s-disease-can-now-be-detected-through-the-skin/ar-BB1kecIH #healthcare #skin #biopsy #abnormal #protein #neurodegenerative

In a new study, Angelika Harbauer & team found that insulin supports the recycling of dysfunctional mitochondria in neurons. Energy scarcity or interrupted insulin signals can lead to the continued use of defective mitochondria, which might affect neurodegenerative diseases. Read more: https://www.bi.mpg.de/news/2024-03-harbauer

Art by @somedonkey

The discovery that a #lipid helps induce #cell #death could improve treatments for certain #cancers and #neurodegenerative diseases. Columbia researchers have found that a rare type of lipid is a key driver of #ferroptosis, a form of cell death
#Biology #sflorg
https://www.sflorg.com/2024/02/bio02152402.html

Protein Associated With Neurodegenerative Diseases Found To Be Linked to Childhood Brain Cancer
https://scitechdaily.com/protein-associated-with-neurodegenerative-diseases-found-to-be-linked-to-childhood-brain-cancer/ #medicine #Neurodegenerative #Diseases #protein #ChildhoodBrainCancer #link

Deer Are Beta-Testing a Nightmare Disease
https://www.theatlantic.com/science/archive/2024/02/deer-chronic-wasting-disease-prions-spillover-people/677307/ #deer #ChronicWastingDisease #CWD #prion #MadCow #fatal #spreading #contagious #neurodegenerative

One protein of polyglutamine folds into a particular shape to start forming the #amyloid that causes #Huntington’s and other #neurodegenerative diseases. #Neuroscience https://elifesciences.org/digests/86939/stick-twist-or-fold?utm_source=mastodon&utm_medium=social&utm_campaign=organic

Gut #microbiota and #neurological effects of #glyphosate

by Lola Rueda-Ruzafa , Francisco Cruz, Pablo Roman, Diana Cardona

August, 2019

"There are currently various concerns regarding certain #environmental #toxins and the possible impact they can have on developmental diseases. #Glyphosate (Gly) is the most utilised #herbicide in #agriculture, although its widespread use is generating controversy in the scientific world because of its probable carcinogenic effect on human cells. Gly performs as an inhibitor of 5-enolpyruvylshikimate-3-phospate synthase (EPSP synthase), not only in plants, but also in bacteria. An inhibiting effect on EPSP synthase from intestinal microbiota has been reported, affecting mainly beneficial bacteria. To the contrary, Clostridium spp. and Salmonella strains are shown to be resistant to Gly. Consequently, researchers have suggested that Gly can cause #dysbiosis, a phenomenon which is characterised by an imbalance between beneficial and pathogenic #microorganisms. The overgrowth of bacteria such as #clostridia generates high levels of noxious metabolites in the #brain, which can contribute to the development of neurological deviations. This work reviews the impact of Gly-induced intestinal #dysbiosis on the central nervous system, focusing on emotional, neurological and #neurodegenerative disorders. A wide variety of factors were investigated in relation to brain-related changes, including highlighting #genetic abnormalities, pregnancy-associated problems, diet, infections, vaccines and heavy metals. However, more studies are required to determine the implication of the most internationally used herbicide, Gly, in behavioural disorders."

https://pubmed.ncbi.nlm.nih.gov/31442459/