It is only a matter of time before the Fediverse starts to self-organise into 'blocs'.
The ad-hoc blocks and defederations of the past will inevitably be superseded by more formal alliances.
Whole areas of the Fediverse will be effectively cut off from each other.
This is perfectly normal and will be a sign that defederated social media is working.
But the period leading up to a more defined shape to the Fediverse will be turbulent and dis-orientating.
Maybe the blocs already exist?